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It is also known as carbamide, is a safe, useful compound with significant history. It is naturally occurring molecule that is produced by protein metabolism. Urea is the most important product of protein degradation and this is the first organic compound artificially synthesized from inorganic starting materials. Urea is used as a chemical intermediate, stabilizer in explosives, medicines and viscosity modifier, plastics, adhesives, pharmaceuticals, cosmetics, dentifrices, flame proofing agents and preparation of burette. Urea is also commonly used in the studies of DNA because it causes uncoiling of DNA molecules.